NATURAL INGRIEDIENTS - MQ knee pain patch is is made of a variety of pure natural plant extracts and is made with a scientific self-heating patch design to provide deep penetrating pain relief for muscle soreness and joint soreness. A total of 24 pieces ( 2 bags/box; 12 pieces/ bag ).PAIN RELIEF - These heat patches for pain relief can relieve various pains such as rheumatoid arthritis, bone hyperplasia, knee pain, tenosynovitis, strain and sprain, sciatica, and fibromyalgia, etc.EASY TO USE - Wipe the painful skin with warm water before each use, tear off the protective film, and stick the pain relief patch on the painful area. We suggest that using for 8-12hours/time, 5 times/week.FAST LASTING PAIN RELIEF - MQ heat patches for knee pain relief has strong penetrating power, quickly heats up, promote blood circulation, fast-acting and effective pain relief up to 12 hours at a time.GUARANTEE - This joint pain relief patch is fast-acting and will work in several minutes. If not, simply return it within 30 days for a full refund.